美国FDA已批准伐昔洛韦（valacyclovir，阿普洛韦的左旋撷氨酸酯，商品名Valtrex）用于口服治疗免疫功能正常成年人的带状疱疹。法普洛韦（famciclovir）也用于这一适应症。1药动学阿昔洛韦口服吸收不完全，其生物利用度仅15～30％劲。而伐昔洛韦吸收较完全，在肠壁及肝脏迅速? The U.S. FDA has approved valacyclovir (L-formate of aplopitol, trade name Valtrex) for the oral treatment of shingles in immunocompetent adults. Famciclovir is also used in this indication. 1 pharmacokinetic acyclovir oral absorption is not complete, its bioavailability of only 15 to 30% of the fresh. And valacyclovir absorbed more completely in the intestinal wall and liver rapidly?