论文部分内容阅读
目的评价脑卒中后抑郁的老年患者早期接受抗抑郁治疗对其神经功能恢复的影响。方法将来我院就诊的60例经过评估、筛查符合脑卒中后抑郁诊断的老年患者的相关资料进行分析，将其随机分成治疗组和对照组。两组患者均接受急性脑卒中的常规治疗，治疗组在常规脑卒中治疗的基础上给予西酞普兰晨起20mg顿服。采用美国国立卫生研究：卒中量表（NIHSS）评分，HAMD评分、GDS评分和Barthel指数，通过对两组患者治疗2w后进行神经功能缺损程度、神经功能恢复比率的评定，对两组患者进行疗效评估。结果2w后治疗组的神经功能恢复比率显著低于对照组(<0.05)。治疗组HAMD、GDS评分明显低于对照组，比较有统计学意义(<0.05)；治疗组BI评分明显高于对照组，比较有统计学意义(<0.05)。结论早期抗抑郁治疗可促进患者神经功能的恢复及可明显改善卒中后抑郁患者的抑郁状态，改善总体预后，提高其生活质量。“,”Objective To evaluate the influence of anti-depression therapy on the rehabilitation of neurological function in elderly patients suf ering acute stroke with post-stroke depression in early stage.Methods Sixty elderly patients were divided into treatment group and control group randomly.Patients in treatment group received routine therapy and Citalopram,and patients in control group received routine therapy only.The ef icacy of the treatment were evaluated by clinical neurological deficit scores,geriatric depression scores and HAMD scores.Results The neurological function deficit scores of the treatment group were significantly lower than those of the control group ( <0.05).The rank sum test indicated that the ef icacy of the treatment group were obviously superior to that of the control group( <0.05).Conclusion The treatment for patients in acute stroke with post-stroke depression in early stage is ef ective for the rehabilitation of neurological function.