为研究榼藤子[Entada phaseoloides(L.)Merr.]种仁的化学成分,利用正反相硅胶柱色谱、制备HPLC分离纯化,通过现代波谱学技术鉴定结构。从70%乙醇提取物的正丁醇萃取部位分离得到4个含硫酰胺类化合物,分别为entadamideA-β-D-glucopyranosyl-(1→3)-β-D-glucopyranoside(1)、entadamideA(2)、entadamideA-β-D-glucopyranoside(3)和clinacosideC(4)。化合物1为新化合物,化合物4为首次从该属中分离得到。 To study the chemical constituents of the seed of Entada phaseoloides (L.) Merr., The constituents were purified by preparative HPLC using silica gel column chromatography and reversed-phase silica gel column chromatography. The structures were identified by modern spectroscopy. Four sulfated amide compounds were isolated from the n-butanol extract of 70% ethanol extract, which were entadamide A -β-D-glucopyranosyl- (1 → 3) -β-D-glucopyranoside ), Entadamide A-β-D-glucopyranoside (3) and clinacoside C (4). Compound 1 is a new compound, and compound 4 is isolated from this genus for the first time.