目的　了解综合医院非精神科医生对抑郁问题的认识 ,为抑郁的诊治工作及医学再教育提供资料与信息。方法　按医院级别分层选点随机抽样获取样本 ,用自编抑郁问题调查问卷进行调查。问卷内容包括抑郁一般知识、临床表现以及相关问题三部分。然后就非精神科医生对抑郁的认识及其相关因素进行对照与分析。结果　共完成调查 346人。抑郁知识平均得分 13 .5 3± 2 .0 8,对抑郁知识条目的应答正确率最高的为 95 .4% ,最低的仅为 14.5 %。抑郁知识得分与医院级别、职称、学历、及对抑郁与非精神科医生关系的认识等因素有关。结论　非精神科医生对抑郁的认识和对抑郁知识的掌握情况急待改善 Objective To understand the non-psychiatrist general hospital’s understanding of depression and to provide information and information on the diagnosis and treatment of depression and medical re-education. Methods The samples were randomly selected according to the stratification points at the hospital level, and were surveyed by using self-compiled questionnaire of depression. Questionnaire content includes general knowledge of depression, clinical manifestations and related issues in three parts. Then the non-psychiatrist’s understanding of depression and its related factors were compared and analyzed. Results A total of 346 people were investigated. The average score of depression knowledge was 13.53 ± 2.08, the highest correct rate of response to depression knowledge items was 95.4%, the lowest was only 14.5%. Depression knowledge score and the hospital level, title, education, and the relationship between depression and non-psychiatrist and other factors. Conclusion Non-psychiatrist’s understanding of depression and mastery of the knowledge of depression urgently need improvement