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目的了解广西结核杆菌/艾滋病病毒(双重感染)双向筛查及防治情况,为今后的防治工作提供科学依据。方法对2014-2016年广西所有市、县(区)的双重感染防治年度报表数据按不同年份、结核病分类、地区分析双向筛查及患者治疗情况。结果 2014-2016年登记的结核病(TB)患者艾滋病病毒(HIV)抗体检测率为85.16%(88 892/105 401),检出率为0.72%(638/88 892);诊断结核前已知HIV阳性1 018例,双重感染比例(含新检出HIV阳性和既往阳性)为1.57%(1 565/105 401),非重点地区的HIV检测率及双重感染比例逐年上升(P<0.001)。新登记HIV感染者/AIDS患者胸部影像学检查或痰涂片查TB的检查率为74.68%(20 808/27 863),重点地区检查率逐年升高(P<0.001);TB检出率为6.46%(1 737/26 903)。各年既往HIV感染者/AIDS患者的TB检出率为1.01%~1.82%。双重感染患者同时抗结核并抗艾滋病病毒药物治疗的综合治疗率为48.30%(2 282/4 725),呈逐年升高趋势;抗结核成功治疗率为81.21%(2 472/3044)。结论广西的结核杆菌/艾滋病病毒双重感染监测和防治工作逐步提高,仍需完善结核病和艾滋病综合服务机制,以提高患者诊治的可及性、治疗率及治疗效果。
Objective To understand the two-way screening and control of Mycobacterium tuberculosis / HIV in Guangxi (double infection) and provide a scientific basis for future prevention and treatment. Methods The data of double infection prevention and control of all cities and counties (districts) in Guangxi in 2014-2016 were collected according to different years, TB classification, regional bi-directional screening and patient treatment. Results The detection rate of HIV antibody among TB patients registered in 2014-2016 was 85.16% (88 892/105 401) with a detection rate of 0.72% (638/88 892). HIV was diagnosed before TB The prevalence of double infection (including newly detected HIV positive and former positive) was 1.57% (1 565/105 401). The HIV detection rate and double infection rate in non-key areas increased year by year (P <0.001). The examination rate of thoracic imaging examination or sputum smear examination of newly registered HIV / AIDS patients was 74.68% (20 808/27 863), the examination rate in key areas increased year by year (P <0.001), the detection rate of TB was 6.46% (1 737/26 903). The detection rate of TB was 1.01% ~ 1.82% in all previous HIV infected persons / AIDS patients. The combined treatment rate of concurrent TB and anti-HIV treatment was 48.30% (2 282/4 725) in patients with dual infection, showing an increasing trend year by year. The successful treatment rate of anti-TB was 81.21% (2 472/3044). Conclusion The surveillance and prevention and control of TB / HIV in Guangxi are gradually increasing. The comprehensive service mechanism of TB and AIDS still needs to be improved so as to improve the accessibility, treatment rate and treatment effect of patients.