微型包囊是将药物包裹于高分子物质中,使之成为密封的微小胶囊。外观呈粒状或园球,直径一般在5～400μ之间。此种微囊能使药物稳定性增高、蔽盖药物的苦味和特臭、防止药物的挥发。还可使药物肠溶或缓释,提高生物利用度。液体药物可以制成微囊而压制片剂。微囊技术还可以解决复方制剂的配伍禁忌问题。微囊技术国外制药公司均有专利,简介如下: 瑞士罗氏药厂的维生素E微囊,直径为20～40μ。将苯甲酸钠5g与山梨酸2g溶于550g蒸馏水中,加热至65℃,加入适量明胶乳化维生素E 550g,然后稀释至含固体量 Microencapsulation is the drug wrapped in high molecular material, making it a sealed capsule. The appearance of granular or garden ball, the diameter is generally between 5 ~ 400μ. Such microcapsules can make the drug more stable, cover the bitter taste of drugs and special smelly, to prevent drug volatilization. Also make the drug enteric-coated or sustained release, improve bioavailability. Liquid drugs can be made into microcapsules to compress the tablets. Microcapsule technology can also solve the problem of incompatibility of compound preparations. Microcapsule technology Foreign pharmaceutical companies have patents, as follows: Switzerland Roche pharmaceutical vitamin E microcapsules, a diameter of 20 ~ 40μ. The sodium benzoate 5g and sorbic acid 2g dissolved in 550g of distilled water, heated to 65 ° C, adding an appropriate amount of gelatinized vitamin E 550g, and then diluted to a solids content