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目的:对米非司酮治疗部分胎盘植入和部分胎盘粘连的临床应用价值进行研究。方法:选择38例部分胎盘植入以及粘连的病人进行了随机分组,分别为对照组以及研究组,对照组主要采用静脉注射20U的缩宫素进行治疗,研究组主要采用米非司酮方法进行治疗,随后对两个组病人治疗之后出血情况以及胎盘的排出时间进行了详细的对比。结果:两组病人经过治疗之后,研究组生产后12小时以及24小时的出血量和对照组出血量比较没有明显的差异(P>0.05);研究组经过治疗后72小时内的出血量远远低于对照组(P<0.05);治疗2周后,研究组阴道流血停止例数多于对照组,胎盘排出时间短于对照组,差异有统计学意义(P<0.05)。结论:对于部分胎盘植入以及粘连来说,米非司酮治疗的临床效果非常好,不但能够在一定程度上使出血风险以及清宫次数降低,而且具有较高的安全性,可广泛的应用到临床实践中。
Objective: To study the clinical value of mifepristone in the treatment of partial placenta accreta and partial placental adhesion. Methods: Thirty-eight patients with partial placenta accreta and adhesion were randomly divided into control group and study group. The control group was treated with intravenous injection of 20U oxytocin. The study group was mainly treated with mifepristone Treatment, followed by a detailed comparison of bleeding after treatment and placental discharge time between the two groups of patients. Results: After two groups of patients were treated, there was no significant difference in the amount of bleeding at 12 hours and 24 hours after birth in the study group compared with that in the control group (P> 0.05). The amount of bleeding within 72 hours after treatment in the study group was far (P <0.05). After 2 weeks of treatment, the number of vaginal bleeding stopped more in the study group than in the control group, and the placental discharge time was shorter than that in the control group (P <0.05). CONCLUSIONS: For some placenta accreta and adhesions, the clinical effect of mifepristone treatment is very good, not only to a certain extent, reduce the risk of bleeding and the reduction of the number of clear-cut, but also has high safety, can be widely used In clinical practice.