早就有人猜想在成熟细胞中可能产生一种调节细胞分化和增殖速度的信号物质。后来,即从上皮等组织中分离和鉴定出一类能抑制其细胞分裂活性的抑制剂。这类物质被命名为抑素(chalone)。近十几年来对它进行了比较广泛而系统的研究。有充分的证据表明这类物质不仅存在于所有正常细胞中,而且依然存在于恶性肿瘤细胞中。一方面 It has long been speculated that in mature cells may produce a signal that regulates the rate of cell differentiation and proliferation. Later, from the epithelium and other tissues isolated and identified a class of inhibitors can inhibit their cell division activity. These substances are named chalone. In the recent ten years it has carried on more extensive and systematic research. There is good evidence that these substances not only exist in all normal cells, but also in malignant cells. on the one hand