抗氧化剂茶多酚对微循环的影响及成因探讨

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Objectives: To study the effects of tea polyphenols(TP) on bulbar conjunctiva microcirculation(BCM) and antioxidation in aircrew and find out the proper antioxidant for the health protection of aircrew. Methods: 40 healthy aircrew were divided into TP group(TP 600 mg/24 h, po) and control group(placebo) randomly. The effects of TP on microcirculation and antioxidation in aircrew were tested after 20 days. Results: The results showed that red blood cell(RBC) superoxide dismutase(SOD) activity and GSH Px(Whole blood glutathione peroxidase)/MDA(serum malondialdehyde) ratio in TP group were significantly higher than those in controls( P < 0.01 ), and serum MDA level was significantly decreased after TP administration( P < 0.05 ). The numbers capillaries and blood flow in microangium were significantly increased, RBC aggregation, ischemia area and A(arteriole)/V(venule) ratio were remarkably decreased in TP group( P < 0.01 ~ 0.05 ). The total integral value of microcirculation in TP group was significantly reduced in comparison with that in the control group. Conclusion: TP can significantly increase the antioxidative ability of aircrew, decrease the BCM disturbance and improve the microcirculatory function. Objectives: To study the effects of tea polyphenols (TP) on bulbar conjunctiva microcirculation (BCM) and antioxidation in aircrew and find out the proper antioxidant for the health protection of aircrew. Methods: 40 healthy aircrew divided into TP group (TP 600 mg The effects of TP on microcirculation and antioxidation in aircrew were tested after 20 days. Results: The results showed that red blood cell (RBC) superoxide dismutase (SOD) activity and GSH Px (Whole blood glutathione peroxidase) / MDA (serum malondialdehyde) ratio in TP group were significantly higher than those in controls Blood flow in microangium were significantly increased, RBC aggregation, ischemia area and A (arteriole) / V (venule) ratio were remarkably decreased in TP group (P <0.01 ~ 0.05). The total integral value of microcirculation n in TP group was significantly reduced in comparison with that in the control group. Conclusion: TP can significantly increase the antioxidant ability of aircrew, decrease the BCM disturbance and improve the microcirculatory function.
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