论文部分内容阅读
肺是骨肉瘤转移的主要靶器官，在应用化疗前， 80％～ 90％的患者死于肺转移。骨转移也有发生，但往往发生于疾病的晚期，常在临床上未被发现或仅见于尸检。辅助化疗和新辅助化疗的应用，大大地提高了骨肉瘤患者的生存率，同时其转移方式也发生了改变。肺外转移的发生率增高，
Lung is the main target organ for osteosarcoma metastasis. Before chemotherapy, 80% to 90% of patients died of lung metastasis. Bone metastasis also occurs, but often occurs in the late stages of the disease, often not found clinically or only at autopsy. The use of adjuvant chemotherapy and neoadjuvant chemotherapy has greatly improved the survival rate of patients with osteosarcoma, and the mode of metastasis has also changed. The incidence of extrapulmonary metastases increased.