中药复方当归饮子治疗慢性荨麻疹的系统评价

来源 :中国实验方剂学杂志 | 被引量 : 0次 | 上传用户:shuang9988
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目的:系统评价中药当归饮子治疗慢性荨麻疹(chronic urticaria,CU)的有效性和安全性.方法:计算机检索PubMed、Embase、Cochrane Central、CBM、CNKI、万方和VIP数据库,搜集当归饮子治疗CU的随机及半随机对照试验,检索时限均从各数据库建库至2013年5月.采用RevMan5.2.5软件进行Meta分析,采用GRADE Profile3.6对结果的证据质量等级进行评价.结果:最终纳入15项试验,共1 358例患者.Meta分析结果显示,当归饮子治疗CU的治愈率、有效率均优于除咪唑斯汀外的常规抗组胺药物(conventional antihistamine,CA);复发率、不良反应发生率均低于CA.结论:本系统评价结果显示,与CA相比,当归饮子有更高的治愈率和有效率,能降低复发率、不良反应发生率.但由于纳入文献质量较低,尚需高质量的多中心大样本随机双盲对照试验来验证.
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