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Rationale:It is well established that the proliferation of vascular smooth muscle cells(VSMCs) has major roles in the vascular remodeling process.We recently reported that microRNA-155 (miR-155)is a key mediator of vascular injury and neointimal hyperplasia.However, the function of miR-155 in VSMCs and its in vivo roles in vascular remodeling remainto be elucidated.