The interaction of GPIb-Ⅸ with VWF incurs platelet activation, apoptosis, and GPIbα ectodomain shedd

来源 :微循环国际研讨会暨第十三届全国中西医结合微循环学术会议(International Conference for Mic | 被引量 : 0次 | 上传用户:ghanfeng
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Under high shear rate flow conditions such as in arteries and capillaries, platelet adhesion to the subendothelium is dependent on interaction between subendothelial-bound von Willebrand factor (VWF) and its receptor, the platelet glycoprotein Ib-Ⅸ-Ⅴ complex (GPIb-Ⅸ-Ⅴ).
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