Active Site Mimicry of Glutathione Peroxidase byGlutathione Imprinted Selenium-Containing Trypsin

来源 :第十一届中国酶工程学术研讨会 | 被引量 : 0次 | 上传用户:BlueDragon8848
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  In order to overcome the instability of natural glutathione peroxidase(GPx),scientistsendeavor to produce GPx mimics.The popular method first uses biological imprinting(BI)toproduce the substrate binding sites and then employs chemical mutation(CM)to obtain thecatalytic site.However,BICM has a drawback in that the catalytic site is not clear.Some researcherstherefore tried to change the order of the method.
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