Pseudo-time reconstruction and evaluation in single-cell RNA-seq analysis

来源 :上海交通大学 | 被引量 : 0次 | 上传用户：datoufangyuan

【摘要】

：

When analyzing single-cell RNA-seq data,constructing a pseudo-temporal path to order cells based on the gradual transition of their transcriptomes is a useful way to study gene expression dynamics in

【作者】

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Hongkai Ji Zhicheng Ji

【机构】

：

Department of Biostatistics,Johns Hopkins University Bloomberg School of Public Health,615 North Wol

【出处】

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上海交通大学

【发表日期】

：

2016年4期

【关键词】

：

High-throughput sequencing single cell genomics minimum spanning tree RNA-seq

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　　When analyzing single-cell RNA-seq data,constructing a pseudo-temporal path to order cells based on the gradual transition of their transcriptomes is a useful way to study gene expression dynamics in a heterogeneous cell population.,Tools for Single Cell Analysis(TSCAN)is a software tool developed to better support in silico pseudo-Time reconstruction in Single-Cell RNA-seq ANalysis.

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Pseudo-time reconstruction and evaluation in single-cell RNA-seq analysis

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