Mixture modeling with applications to integrative analysis of post-mortem tissue studies in schizoph

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  Due to the many possible combinations of symptoms, schizophrenia is clinically thought not to be a homogeneous disease, so that this possible heterogeneity might be explained neurobiologically.The ultimate goal of our statistical research is to cluster subjects with schizophrenia into possible heterogeneity groups.But, in attempting to combine databases from multiple post-mortem tissue studies in the Conte Center for the Neuroscience of Mental Disorders at the University of Pittsburgh, several experimental specifics, including differing control subjects, effects of covariates and
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