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By using RNA-Seq,we investigated transcriptome analysis in developing leaves and panicles of three hybrids and their parents with different levels of yield advantage.Hierarchical clustering analysis of all genes revealed that three hybrids and their parents had nearly identical transcriptomic patterns at the same growth stage.The great numbers of differential expression genes(DEGs)were found between hybrid XA/WD7 with its parents(3589)at three stages by transcriptomic analysis,second is XA/WD34 and its parents(3146),and last is XA/SH527 and its parents(2912).