Study on antioxidant activity and immune effects of Anthriscus sylvestris extracts

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  We engaged in studies on antioxidant activity of total flavonoids and immunomodulatory effect of polysaccharide in anthriscus sylvestris.Concentration of total flavonoids in 27.5μg/ml-800μg/ml, the scavenging of hydroxyl radicals and the inhibition of superoxide anion showed a dose-effect relationship, and in the concentration of 800μg/ml department, the maximum clearance and inhibition rates were 32.88% and 24.87%; compared with the control group, high dose (62.5mg/kg) of Anthriscus sylvestris flavonoids can significantly enhance the spleen and kidney tissues SOD activity, but decrease MDA content at the same time.The high dose polysaccharide (200mg/kg) from Anthriseus sylvestris significantly increased the spleen index, liver index, clearance index and phagocytic index.The results have indicated that the Anthriscus sylvestris flavonoids have a good antioxidant activity in vivo and vitro, and also the polysaccharide has a good effect in immune regulation.
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