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Background: Protein is the material basis of life, it is a major activity executor.Apoptosis proteins play a very important role in the growth and development of the human body.It is associated with many diseases.During apoptosis the anti-apoptosis and pro-apoptosis perform different function in the regulation of apoptosis.If the inactivation of anti-apoptosis proteins or pro-apoptosis proteins, it will lead to the occurrence of cancer and other diseases.So the classification of anti-apoptotic proteins and pro-apoptotic proteins will help us understand the pathogenic mechanism of the apoptosis proteins better.