Perineuronal nets(PNs)are implicated in controlling neural plasticity during neuronal circuit formation in the postnatal CNS.With negative geotaxis as a readout of postnatal maturation of the vestibul
Akt(protein kinase B)plays important roles in various biological processes.Recent evidence has shown that mutations on Akt3 are associated with brain developmental diseases.
Methyl-CpG binding protein 2(MeCP2)plays critical roles in transcriptional regulation and microRNA processing.Mutations in MECP2 gene are found in 90%of patients with Rett syndrome,a severe form of de
Autism spectrum disorders(ASD)are characterized by some core features,including markedly abnormal or impaired social interaction and communication,restricted interests,and stereotypical behaviors.
For a long time,researches on energy metabolism and emotion regulation are divided in their respective fields.However,epidemiological investigations suggest that metabolic diseases like obesity and mo
Objective The innate ability of animals to respond to life-threatening stimuli is essential for survival.These stimuli activate modular brain circuits consisting of phylogenetically ancient subcortica