Interaction between beta subunits and extracellular matrix mo dulating sodium channels-involved mirr

来源 :第12届生物毒素研究及医药应用学术大会 | 被引量 : 0次 | 上传用户:liulg
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  Voltage-gated sodium (Nav) channels play key roles in induction, transmission,transduction of pathological pain.Nay channels are composed of a pore-forming αt subunit and associated β subunits.Each of β subunit (β1-β4) is a single membrane-spanning glycoprotein with one Ig-like motif in their extracellular domains, which may bind to Chondroitin sulfate proteoglycans (CSPGs).
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