Targeted MRI contrast agent based on hyperbranched lipopolymer hybrids

来源 :Fourth Symposium on Innovative Polymers for Controlled Deliv | 被引量 : 0次 | 上传用户:catknight
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  MnFe2O4 magnetic nanoparticles (MNPs) are powerful negative contrast agents due to their outstanding properties such as superparamagnetic behavior,and high saturation magnetization[1].In this study,we have designed MNPs not only for high magnetic resonance (MRI) contrast enhancement but also for excellent colloidal stability in water and targeting capability to use in medical applications.
其他文献
本文采用介孔SiO2阴离子表面活性剂成型机理S- N+I-,用月桂酸代替阴离子表面活性剂直接生成带氨基的介孔SiO2来吸附CO2.采用红外、XRD/HRTEM对其表征,测量其CO2吸附量最大为1.40mmol·g-1,在100℃解吸,发现经过多次吸附/解吸循环后基本保持CO2吸附特性不变.
木质纤维素是地球上最丰富的可再生生物质资源,其中纤维素和半纤维素的高效酶解糖化是木质纤维素生物精炼的关键环节.近年来,为了提高木质纤维素酶解效率,各国学者围绕预处理方式确定及酶解制约因素分析等方面开展了大量研究.本文对近年来在确定木质纤维素酶解的关键底物特性方面取得的最新研究成果进行了综述和分析,主要包括:不同预处理过程中木质纤维素底物特性的变化以及不同底物特性对纤维素酶水解的影响.由于木质纤维索
介绍了以二氧化碳为原料合成甲醇、尿素以及二氧化碳与环氧乙烷、甲醇、尿素直接进行反应合成碳酸酯的研究进展情况.以二氧化碳为原料合成甲醇、碳酸酯是减少温室气体和利用碳资源的最有效途径.
Proteins play crucial functions inside cells and are promising tools for medical applications,including disease therapies,vaccination,and imaging[1].From a therapeutic perspective,protein-based therap
Supramolecular assemblies of protein/peptide play important roles in living organisms.Inspired by these natural structures,many protein/peptide supramolecular assemblies have been constructed with new
Cancer stem cells (CSCs) have the capability to initiate tumor,to sustain tumor growth,to maintain the heterogeneity of tumor,and are closely linked to the failure of chemotherapy due to their self-re
Polymer has acted as the backbone to support the development of pharmaceutics during the past several decades.The first and foremost objective of drug solid dispersion (SD) is to solve the problems as
Bacterial infection has been a major reason for the failure ofbiomaterials or biomedical devices in vivo.Thus there has been a great demand for biomaterials with antibacterial property.Owing to the br
The expression level of specific enzymes like matrix metalloproteases (MMPs) is often higher in tumor than in normal tissues,which can be exploited for enzyme-responsive cancer therapy,including cance
Nowadays,novel vaccine adjuvant has been urgently required to augment resultant immune responses due to the weak immunogenicity of the emerging vaccines,such as recombinant proteins,protein subunits o