Global mapping transcriptional start sites revealed both transcriptional and post-transcriptional re

来源 :2015年中国微生物学会学术年会 | 被引量 : 0次 | 上传用户:zhangyuhan13
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Psychrophilic methanogenic Archaea contribute significantly to global methane emission,but archaeal cold adaptation mechanisms remain poorly understood.Hinted by the previous observations that mRNA secondary structures respond to cold more promptly than proteins,mRNA architecture-based regulation can contribute to cold adaptation.Using differential RNA-seq,we obtained the transcription start sites (TSS) map for a psychrophilic methanogenic archaeon Methanolobus psychrophilus R15,which revealed the genome-wide unique transcript architectures and cold-responsive dynamic transcription.
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