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An aquatic actinomycete capable of eliminating the brown tide causing marine alga Phaeocystis globosa was isolated from the surface sea water and the isolate named JS01 was characterized as Streptomyces on the basis of its 16S rDNA sequence.The supernatant of JS01 could lyse algal cells,implying that JS01 produced a latent alga-lytic compound.Considering this algicidal activity and the response of the algal cells,Chlorophyll a fluorescence decreased significantly in P globosa in response to the JS01 supematant when analyzed with flow cytometry.