Switching from Morphine to Fentanyl Attenuated the Decline of μ-Opioid Receptor Expression in Periaq

来源 :中华医学会第22次全国麻醉学术年会 | 被引量 : 0次 | 上传用户:AKDelphi
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Opioid switching is a therapeutic maneuver as a method of improving analgesic response and/or reducing adverse side effects1.The iμ-opioid receptor (MOR) has important role in mediating the actions of morphine and other analgesic agents2.This study is aimed to explore the changes of MOR in the periaqueductal gray (PAG) in rats when morphine is substituted with equianalgesic fentanyl.
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