【摘 要】
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The receptive field is one of the most common ways to characterize the function of a neuron in a sensory system.To encode sensory stimuli,cells typically collect information across their receptive fie
【机 构】
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Department of Ophthalmology,University Medical Center G(o)ttingen and Bernstein Center for Computati
【出 处】
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第九届海内外华人神经科学家研讨会(The 9th Symposium for Chinese Neuroscientis
论文部分内容阅读
The receptive field is one of the most common ways to characterize the function of a neuron in a sensory system.To encode sensory stimuli,cells typically collect information across their receptive fields from multiple presynaptic neurons.In the retina,individual ganglion cells receive many excitatory inputs from upstream bipolar cells,which are thought to constitute nonlinear subunits within the ganglion cells receptive field.To date,a systematic method for detecting these subunits without detailed measurements of the anatomical and physiological properties of the bipolar-ganglion cell circuitry is still lacking.In this talk,I present such a novel method,termed spike-triggered non-negative matrix factorization(STNMF),to achieve this goal.I show that knowledge about the subunit locations is important for predicting ganglion cell responses to natural images.These analyses reveal the detailed layout of functional connectivity between two subsequent layers of signal processing in a sensory neural network.
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