Over past years,chiral phosphines have emerged as powerful nucleophilic catalysis and ligands for transition metal catalysis.Despite many types of privileged phosphine ligands and catalysts have been developed,the design and synthesis of novel types of chiral phosphine to address the enantioselectivity of unsolved reactions and substrates is still highly desired,especially those could be easily synthesized from readily available starting materials.Since 2014,we have developed a series of novel types of chiral sulfinamidephosphines(Sadphos)from the inexpensive tert-butanesulfinamde,,which have shown good performance in metal-catalyzed asymmetric cycloadditions,cyclization,cross-coupling,cascade Heck and related reaction and phosphine-catalyzed intra-or intermolecular R-C reactions and diverse reactions(Figure 1).